A study of Alaska's Yup'ik Eskimos, who consume 20 times more omega-3 fats from fish than most Americans, suggests these oils can prevent obesity-related illness such as diabetes and heart disease, researchers said Friday.
The researchers analyzed data from 330 people living in the Yukon Kuskokwim Delta region of southwest Alaska.
Although 70 percent of the population was overweight or obese, they did not show the same risk factors for heart disease and had a lower prevalence of diabetes than the overall US population.
The fats the researchers were interested in measuring were those found in salmon, sardines and other fatty fish -- docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA).
In participants with low blood levels of these fats, obesity strongly increased heart disease risk measured by triglycerides and C-reactive protein, a measure of overall body inflammation.
Additionally, the researchers said that although the Yup'ik Eskimos have overweight/obesity levels similar to those in the US overall, their prevalence of type 2 diabetes is significantly lower -- 3.3 percent versus 7.7 percent.
"Because Yup'ik Eskimos have a traditional diet that includes large amounts of fatty fish and have a prevalence of overweight or obesity that is similar to that of the general US population, this offered a unique opportunity to study whether omega-3 fats change the association between obesity and chronic disease risk," said Zeina Makhoul, a researcher at the Fred Hutchinson Cancer Research Center and lead author.
"Interestingly, we found that obese persons with high blood levels of omega-3 fats had triglyceride and CRP concentrations that did not differ from those of normal-weight persons," Makhoul said.
"It appeared that high intakes of omega-3-rich seafood protected Yup'ik Eskimos from some of the harmful effects of obesity."
The study was led by researchers at Fred Hutchinson Cancer Research Center and conducted in collaboration with the Center for Alaska Native Health Research at the University of Alaska-Fairbanks. It published online March 23 in the European Journal of Clinical Nutrition.
For the study, the participants provided blood samples and health information via in-person interviews and questionnaires. Diet was assessed by asking participants what they ate in the past 24 hours and asking them to keep a food log.
The researchers said however that further studies would be needed to make specific recommendations on diets or supplements.
"If the results of such a trial were positive, it would strongly suggest that omega-3 fats could help prevent obesity-related diseases such as heart disease and diabetes," Makhoul said.
2011. április 22., péntek
2011. február 16., szerda
Fish Oil: Good For Vision
Grab some walnuts and a plate of fish, new research shows fish oil Omega-3 fatty acids found in these foods may keep you seeing straight.
Past research has shown that Omega 3's may help prevent human blindness, but a new study in mice reveals exactly how that works.
Omega-3 fatty acids are fats commonly found in fish oil. Several years ago researchers at Children's Hospital Boston determined that the fatty acids helped to prevent retinopathy, which is a major form of blindness that affects diabetics and premature babies. That same team conducted this follow up study.
For the study researchers fed mice a diet high in omega-3 fatty acids, and found it prevented abnormal blood vessel growth in the retina. That means omega 3’s could help prevent eye diseases like retinopathy, which are caused by an overgrowth of leaky blood vessels in the eyes.
The researchers also found the benefits of omega-3’s are not affected by drugs such as aspirin or other painkillers. This is good news for diabetics who take aspirin to prevent heart disease.
“The ability to prevent these neovascular eye diseases with omega-3 fatty acids could provide tremendous cost savings, Lois Smith, M.D., Ph.D., senior investigator on the study, was quoted as saying. "The cost of omega-3 supplementation is about $10 a month, versus up to $4,000 a month for anti-VEGF therapy. " she said, referring to drugs such as Macugen and Lucentis used in AMD and diabetic retinopathy. "Our new findings give us new information on how omega-3s work that makes them an even more promising option."
The fatty acids also activated proteins that improve insulin sensitivity. Those proteins are the same ones targeted by type 2 diabetes drugs. This means omega 3's could also be used to improve insulin sensitivity in people with diabetes or pre-diabetes.
Source: Science Translational Medicine, February 14, 2011
Past research has shown that Omega 3's may help prevent human blindness, but a new study in mice reveals exactly how that works.
Omega-3 fatty acids are fats commonly found in fish oil. Several years ago researchers at Children's Hospital Boston determined that the fatty acids helped to prevent retinopathy, which is a major form of blindness that affects diabetics and premature babies. That same team conducted this follow up study.
For the study researchers fed mice a diet high in omega-3 fatty acids, and found it prevented abnormal blood vessel growth in the retina. That means omega 3’s could help prevent eye diseases like retinopathy, which are caused by an overgrowth of leaky blood vessels in the eyes.
The researchers also found the benefits of omega-3’s are not affected by drugs such as aspirin or other painkillers. This is good news for diabetics who take aspirin to prevent heart disease.
“The ability to prevent these neovascular eye diseases with omega-3 fatty acids could provide tremendous cost savings, Lois Smith, M.D., Ph.D., senior investigator on the study, was quoted as saying. "The cost of omega-3 supplementation is about $10 a month, versus up to $4,000 a month for anti-VEGF therapy. " she said, referring to drugs such as Macugen and Lucentis used in AMD and diabetic retinopathy. "Our new findings give us new information on how omega-3s work that makes them an even more promising option."
The fatty acids also activated proteins that improve insulin sensitivity. Those proteins are the same ones targeted by type 2 diabetes drugs. This means omega 3's could also be used to improve insulin sensitivity in people with diabetes or pre-diabetes.
Source: Science Translational Medicine, February 14, 2011
2011. január 11., kedd
Fish oil omega 3 and rheumatoid arthritis
Fish oils appear to relieve the symptoms of rheumatoid arthritis, and this is commensurate with the role of Fish oil omega 3 fatty acids in suppression of the production of inflammatory eicosanoids. Some reports have publicized that very long chain omega 3 fatty acids decrease pain and morning stiffness and decrease the require for NSAIDs. Furthermore, a meta-analysis of 10 double-blind, placebo-controlled randomised trials in 395 patients confirmed that fish oil taken for three months was associated with a statistically significant reduction in joint tenderness and morning stiffness, however no significant improvements in joint swelling, grip strength or erythrocyte sedimentation rate (ESR, a marker of inflammation). On the other hand, a US review carried out for the Office of Dietary Supplements, National Institutes of Health, on the effects of omega-3 fatty acids on rheumatoid arthritis concluded that from nine studies reporting outcomes in patients with rheumatoid arthritis, fish oil omega 3 fatty acids had no effect on patient reports of pain, swollen joint count, ESR and patients’ global assessment by meta-analysis. A Dutch double-blind, placebo-controlled, parallel-group research in 66 patients with rheumatoid arthritis using 1.4 g EPA, 0.211 g DHA and 0.5 g gamma-linolenic acid (GLA) with micronutrients discovered no significant modification from baseline in tender joint count, swollen joint count, visual analogue scales for pain and disease activity, grip strength, functionality scores and morning stiffness. The conclusion was that this research adds information regarding doses of fish oil omega-3 fatty acids below which antiinflammatory effects in rheumatoid arthritis aren't seen.
2011. január 9., vasárnap
How much Omega 3 is in the fish oil containing products?
Here you can find a list of omega 3 (EPA and DHA) content of different fish oil containing products. The Fish oil omega 3 contet of different fishes can be different.
The 3 value are the following:
1. Name of food
2. Average serving (g)
3. Totel EPA and DHA per serving (g)
Kippers 130; 3.37
Mackerel 160; 3.09
Pilchards (canned in tomato sauce) 110; 2.86
Trout 230; 2.65
Salmon (fresh) 100; 2.2
Sardines (canned in tomato sauce) 100; 1.67
Herring 119; 1.56
Salmon (canned in brine, drained) 100; 1.55
Crab (canned) 85; 0.85
Plaice 130; 0.39
Tuna, fresh 120; 0.3–1.5
Cod 120; 0.30
Mussels 40; 0.24
Haddock 120; 0.19
Tuna (canned in oil, drained) 45; 0.17
Tuna (canned in brine, drained) 45; 0.08
Prawns 60; 0.06
Cod liver oil liquid 10 ml; 1.5–3.0
Cod liver oil capsules Varies; 0.1–0.4
Fish oil capsules Varies; 0.1–0.4
So you can see thet differet fishes fish oil Omega 3 content is quite different.
The 3 value are the following:
1. Name of food
2. Average serving (g)
3. Totel EPA and DHA per serving (g)
Kippers 130; 3.37
Mackerel 160; 3.09
Pilchards (canned in tomato sauce) 110; 2.86
Trout 230; 2.65
Salmon (fresh) 100; 2.2
Sardines (canned in tomato sauce) 100; 1.67
Herring 119; 1.56
Salmon (canned in brine, drained) 100; 1.55
Crab (canned) 85; 0.85
Plaice 130; 0.39
Tuna, fresh 120; 0.3–1.5
Cod 120; 0.30
Mussels 40; 0.24
Haddock 120; 0.19
Tuna (canned in oil, drained) 45; 0.17
Tuna (canned in brine, drained) 45; 0.08
Prawns 60; 0.06
Cod liver oil liquid 10 ml; 1.5–3.0
Cod liver oil capsules Varies; 0.1–0.4
Fish oil capsules Varies; 0.1–0.4
So you can see thet differet fishes fish oil Omega 3 content is quite different.
2011. január 6., csütörtök
Fish Oil May Help Some Heart Failure Patients (omega 3)
New fish oil omega 3 supplement results:
Omega-3 fatty acid supplements seem to boost heart function, study finds
For heart failure patients whose condition is controlled with standard care, omega-3 fatty acid supplements appear to improve their condition even more, a small study suggests.
"Adding n-3 polyunsaturated fatty acids, even in patients that had a major improvement [on standard treatment], showed a further improvement in heart function and exercise capacity," said study co-author Dr. Mihai Gheorghiade, a professor of cardiology at Northwestern University's Feinberg School of Medicine.
This shows that even in patients who respond to therapy, "we can make them much better," he added. "This opens the door for the potential of a natural therapy -- so-called macronutrients -- in the management of heart failure."
Gheorghiade cautioned that this study is not conclusive, but nutrients such as omega-3 fatty acids might extend life and quality of life for these patients.
The report is published in the Jan. 5 online edition of the Journal of the American College of Cardiology.
Gheorghiade's team randomly assigned 133 heart failure patients with minimal symptoms on standard therapy, which included beta blockers, to high doses (2 grams) of omega-3 fatty acid supplements or a placebo.
After a year, those receiving the omega-3 supplement showed a 10.4 percent increase in heart function, compared with a 5 percent decrease among those taking placebo, the researchers found.
In addition, blood oxygen levels increased 6.2 percent in the omega-3 patients and decreased 4.5 percent in the placebo patients. Also, exercise time went up 7.5 percent in those receiving supplements while it went down 4.8 percent in those receiving placebo, they added.
Moreover, among those taking the supplement the hospitalization rate was 6 percent during the year, compared with 30 percent for those on placebo.
Gheorghiade speculated that the supplements improved the metabolism of the heart. "This is one example where a nontraditional therapy may also work," he said.
However, larger studies are needed to really see if this supplement helps prolong life, Gheorghiade said. "It's promising, but it's not conclusive," he said. "But it would be a mistake not to look at the value of the macro and micronutrients in the management of heart failure."
Gheorghiade doesn't recommend that people take large amounts of this supplement in hopes of staving off heart disease. Whether or not one should take a supplement is a topic that patients and their doctors should discuss, he said.
Treatment needs to be tailored to individual patients, he pointed out. "This is not a cookbook," Gheorghiade added.
Dr. W.H. Wilson Tang, an assistant professor of medicine at the Cleveland Clinic and co-author of an accompanying journal editorial, said that "studies on omega-3 fatty acid in heart failure still have not been effectively tested, based on limitations on their designs."
Tang added, "We need to know what are potential dose and timing of intervention before we can effectively demonstrate whether an intervention works or not."
The current study suggested that doses far higher than commonly used may have some effect not seen in the larger studies, he said.
"That being said, whether every treatment approach needs mega-trials to demonstrate effectiveness is now being increasingly challenged. The current debate is whether a relatively safe intervention such as fish oil should be recommended based on the current data -- it is currently written in some guidelines but not too many doctors are actively recommending them," Tang said.
Douglas "Duffy" MacKay, vice president for scientific and regulatory affairs at the Council for Responsible Nutrition, which represents the supplement industry, said that "all adults should get 500 milligrams of omega-3 fatty acids, from either diet or supplements, just to maintain heart health."
The American Heart Association also recommends that people get omega-3 fatty acids for heart health, with at least two servings a week of fatty fish, such as tuna, sardines or salmon, mackerel, herring or lake trout.
More information
For more information on heart failure, visit the American Heart Association.
Omega-3 fatty acid supplements seem to boost heart function, study finds
For heart failure patients whose condition is controlled with standard care, omega-3 fatty acid supplements appear to improve their condition even more, a small study suggests.
"Adding n-3 polyunsaturated fatty acids, even in patients that had a major improvement [on standard treatment], showed a further improvement in heart function and exercise capacity," said study co-author Dr. Mihai Gheorghiade, a professor of cardiology at Northwestern University's Feinberg School of Medicine.
This shows that even in patients who respond to therapy, "we can make them much better," he added. "This opens the door for the potential of a natural therapy -- so-called macronutrients -- in the management of heart failure."
Gheorghiade cautioned that this study is not conclusive, but nutrients such as omega-3 fatty acids might extend life and quality of life for these patients.
The report is published in the Jan. 5 online edition of the Journal of the American College of Cardiology.
Gheorghiade's team randomly assigned 133 heart failure patients with minimal symptoms on standard therapy, which included beta blockers, to high doses (2 grams) of omega-3 fatty acid supplements or a placebo.
After a year, those receiving the omega-3 supplement showed a 10.4 percent increase in heart function, compared with a 5 percent decrease among those taking placebo, the researchers found.
In addition, blood oxygen levels increased 6.2 percent in the omega-3 patients and decreased 4.5 percent in the placebo patients. Also, exercise time went up 7.5 percent in those receiving supplements while it went down 4.8 percent in those receiving placebo, they added.
Moreover, among those taking the supplement the hospitalization rate was 6 percent during the year, compared with 30 percent for those on placebo.
Gheorghiade speculated that the supplements improved the metabolism of the heart. "This is one example where a nontraditional therapy may also work," he said.
However, larger studies are needed to really see if this supplement helps prolong life, Gheorghiade said. "It's promising, but it's not conclusive," he said. "But it would be a mistake not to look at the value of the macro and micronutrients in the management of heart failure."
Gheorghiade doesn't recommend that people take large amounts of this supplement in hopes of staving off heart disease. Whether or not one should take a supplement is a topic that patients and their doctors should discuss, he said.
Treatment needs to be tailored to individual patients, he pointed out. "This is not a cookbook," Gheorghiade added.
Dr. W.H. Wilson Tang, an assistant professor of medicine at the Cleveland Clinic and co-author of an accompanying journal editorial, said that "studies on omega-3 fatty acid in heart failure still have not been effectively tested, based on limitations on their designs."
Tang added, "We need to know what are potential dose and timing of intervention before we can effectively demonstrate whether an intervention works or not."
The current study suggested that doses far higher than commonly used may have some effect not seen in the larger studies, he said.
"That being said, whether every treatment approach needs mega-trials to demonstrate effectiveness is now being increasingly challenged. The current debate is whether a relatively safe intervention such as fish oil should be recommended based on the current data -- it is currently written in some guidelines but not too many doctors are actively recommending them," Tang said.
Douglas "Duffy" MacKay, vice president for scientific and regulatory affairs at the Council for Responsible Nutrition, which represents the supplement industry, said that "all adults should get 500 milligrams of omega-3 fatty acids, from either diet or supplements, just to maintain heart health."
The American Heart Association also recommends that people get omega-3 fatty acids for heart health, with at least two servings a week of fatty fish, such as tuna, sardines or salmon, mackerel, herring or lake trout.
More information
For more information on heart failure, visit the American Heart Association.
Fish oil won't accelerate weight loss
A news about Fish oil omega 3 containing capsules:
NEW YORK (Reuters Health) – Fish oil capsules won't help boost weight loss if you're already dieting and exercising, new research in the American Journal of Clinical Nutrition shows.
Among a group of overweight and obese adults enrolled in a diet and exercise program, those who took omega 3 fatty acids didn't lose any more weight than those given placebo capsules, Dr. Laura F. DeFina of The Cooper Institute in Dallas and her colleagues found.
There is evidence from animal studies that omega 3 fatty acids promote weight loss, DeFina and her team note, while studies in people have had mixed results. Because fish oil has many other potential health benefits (Fish oil benefits), including cutting cholesterol, improving insulin sensitivity, and reducing blood pressure, "weight-loss programs associated with the use of omega-3 polyunsaturated fatty acids seemed appropriate," they write.
To investigate whether fish oil enhanced the results of a diet and exercise regime, the researchers randomly assigned 128 sedentary overweight or obese men and women to take five fish oil capsules (providing a total of three grams of omega 3 fatty acids) or five placebo capsules every day for 24 weeks.
Participants were also instructed to do 150 minutes a week of aerobic exercise and 20 to 30 minutes of strength exercises at least twice a week.
The people in the omega-3 group lost 5.2 kilograms, or about 11.5 pounds, on average, compared to 5.8 kilograms (nearly 13 pounds) for the placebo group, not a statistically significant difference. People in both groups lost more than five percent of their body weight, enough to produce health benefits.
At the end of the study, there was no difference between the groups in measures of heart disease risk, such as blood pressure and cholesterol levels. However, omega-3 blood levels in the fish oil group increased to a level "previously found to have a positive cardiovascular effect," the researchers note.
Not everyone actually completed the 24-week program; there were only 81 participants at the end. But the results were similar when the researchers looked only at those 81 people.
"Whereas one may not enhance weight loss by taking supplements with this level of omega 3 fatty acids," they write, "the protective cardiovascular effect should still be realized because of the sheer increase in blood concentrations of the fatty acids."
Source: http://www.mb.com.ph/articles/295009/fish-oil-wont-accelerate-weight-loss
NEW YORK (Reuters Health) – Fish oil capsules won't help boost weight loss if you're already dieting and exercising, new research in the American Journal of Clinical Nutrition shows.
Among a group of overweight and obese adults enrolled in a diet and exercise program, those who took omega 3 fatty acids didn't lose any more weight than those given placebo capsules, Dr. Laura F. DeFina of The Cooper Institute in Dallas and her colleagues found.
There is evidence from animal studies that omega 3 fatty acids promote weight loss, DeFina and her team note, while studies in people have had mixed results. Because fish oil has many other potential health benefits (Fish oil benefits), including cutting cholesterol, improving insulin sensitivity, and reducing blood pressure, "weight-loss programs associated with the use of omega-3 polyunsaturated fatty acids seemed appropriate," they write.
To investigate whether fish oil enhanced the results of a diet and exercise regime, the researchers randomly assigned 128 sedentary overweight or obese men and women to take five fish oil capsules (providing a total of three grams of omega 3 fatty acids) or five placebo capsules every day for 24 weeks.
Participants were also instructed to do 150 minutes a week of aerobic exercise and 20 to 30 minutes of strength exercises at least twice a week.
The people in the omega-3 group lost 5.2 kilograms, or about 11.5 pounds, on average, compared to 5.8 kilograms (nearly 13 pounds) for the placebo group, not a statistically significant difference. People in both groups lost more than five percent of their body weight, enough to produce health benefits.
At the end of the study, there was no difference between the groups in measures of heart disease risk, such as blood pressure and cholesterol levels. However, omega-3 blood levels in the fish oil group increased to a level "previously found to have a positive cardiovascular effect," the researchers note.
Not everyone actually completed the 24-week program; there were only 81 participants at the end. But the results were similar when the researchers looked only at those 81 people.
"Whereas one may not enhance weight loss by taking supplements with this level of omega 3 fatty acids," they write, "the protective cardiovascular effect should still be realized because of the sheer increase in blood concentrations of the fatty acids."
Source: http://www.mb.com.ph/articles/295009/fish-oil-wont-accelerate-weight-loss
2011. január 4., kedd
Fish oil benefits
The fish oil Omega 3 content hs a lot of effect on the human body, the fish oil benefits list is long. Te fish oil benefits can be the following.
Fish oil appears to reduce the risk of CHD (coronary heart disease). It may help to: reduce the risk of thrombosis by increasing bleeding tendency; reduce blood levels of triacylglycerols; prevent atherosclerosis and arrhythmias; and reduce blood pressure. Fish oil could have beneficial effects in inflammatory conditions such as rheumatoid arthritis, Crohn’s disease and inflammatory bowel disorders, but evidence of benefit in asthma and psoriasis is poor. Fish oil may have a role in various mental disorders, such as depression, schizophrenia and Alzheimer’s disease, but research in this area is in its infancy. Evidence of benefit of fish oil in maternal and child health, including child development and visual acuity, is conflicting. Evidence of value of omega 3 fatty acids in childhood behavioural disorders, such as developmental coordination disorder, is increasing.
The fish oil omega 3 content (EPA/DHA) can be connected to a lot of fish oil benefits.
Fish oil appears to reduce the risk of CHD (coronary heart disease). It may help to: reduce the risk of thrombosis by increasing bleeding tendency; reduce blood levels of triacylglycerols; prevent atherosclerosis and arrhythmias; and reduce blood pressure. Fish oil could have beneficial effects in inflammatory conditions such as rheumatoid arthritis, Crohn’s disease and inflammatory bowel disorders, but evidence of benefit in asthma and psoriasis is poor. Fish oil may have a role in various mental disorders, such as depression, schizophrenia and Alzheimer’s disease, but research in this area is in its infancy. Evidence of benefit of fish oil in maternal and child health, including child development and visual acuity, is conflicting. Evidence of value of omega 3 fatty acids in childhood behavioural disorders, such as developmental coordination disorder, is increasing.
The fish oil omega 3 content (EPA/DHA) can be connected to a lot of fish oil benefits.
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